Sophia Axt (Schaefer) was 14 years old when Louis Pasteur successfully tests his vaccine against rabies on Joseph Meister, a boy who was bitten by a rabid dog. Louis Pasteur was a French biologist, microbiologist and chemist renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization. He is remembered for his remarkable breakthroughs in the causes and prevention of diseases, and his discoveries have saved many lives ever since. He reduced mortality from puerperal fever, and created the first vaccines for rabies and anthrax. His medical discoveries provided direct support for the germ theory of disease and its application in clinical medicine. He is best known to the general public for his invention of the technique of treating milk and wine to stop bacterial contamination, a process now called pasteurization. He is regarded as one of the three main founders of bacteriology, together with Ferdinand Cohn and Robert Koch, and is popularly known as the "father of microbiology".
Sophia Axt (Schaefer) was 27 years old when Spanish–American War: The Treaty of Paris is signed, officially ending the conflict. The Spanish–American War was fought between the United States and Spain in 1898. Hostilities began in the aftermath of the internal explosion of the USS Maine in Havana Harbor in Cuba, leading to US intervention in the Cuban War of Independence. American acquisition of Spain's Pacific possessions led to its involvement in the Philippine Revolution and ultimately in the Philippine–American War.
Sophia Axt (Schaefer) was 32 years old when The Wright brothers make their first attempt to fly with the Wright Flyer at Kitty Hawk, North Carolina. The Wright brothers, Orville and Wilbur, were two American aviators, engineers, inventors, and aviation pioneers who are generally credited with inventing, building, and flying the world's first successful airplane. They made the first controlled, sustained flight of a powered, heavier-than-air aircraft on December 17, 1903, four miles south of Kitty Hawk, North Carolina. In 1904–05 the brothers developed their flying machine into the first practical fixed-wing aircraft. Although not the first to build experimental aircraft, the Wright brothers were the first to invent aircraft controls that made fixed-wing powered flight possible.
Sophia Axt (Schaefer) was 46 years old when Tsar Nicholas II of Russia was forced to abdicate in the February Revolution, ending three centuries of Romanov rule. Nicholas II or Nikolai II, known as Saint Nicholas in the Russian Orthodox Church, was the last Emperor of Russia, ruling from 1 November 1894 until his forced abdication on 15 March 1917. His reign saw the fall of the Russian Empire from one of the foremost great powers of the world to economic and military collapse. He was given the nickname Nicholas the Bloody or Vile Nicholas by his political adversaries due to the Khodynka Tragedy, anti-Semitic pogroms, Bloody Sunday, the violent suppression of the 1905 Russian Revolution, the executions of political opponents, and his perceived responsibility for the Russo-Japanese War (1904-1905). Soviet historians portray Nicholas as a weak and incompetent leader whose decisions led to military defeats and the deaths of millions of his subjects.
Sophia Axt (Schaefer) was 57 years old when Walt Disney character Mickey Mouse premieres in his first cartoon, "Plane Crazy". Walter Elias Disney was an American entrepreneur, animator, voice actor and film producer. A pioneer of the American animation industry, he introduced several developments in the production of cartoons. As a film producer, Disney holds the record for most Academy Awards earned by an individual, having won 22 Oscars from 59 nominations. He was presented with two Golden Globe Special Achievement Awards and an Emmy Award, among other honors. Several of his films are included in the National Film Registry by the Library of Congress.
Sophia Axt (Schaefer) died on 3 Feb 1933 at the age of 62